INSERM Workshop : Human Pluripotent Stem Cells March 8-10th, 2009

The French Institute for Health Research INSERM organizes a Workshop on human pluripotent stem cells on the French Riviera open to all research staff (Investigators, PhD students, Postdocs...). This is a unique opportunity to meet outstanding international experts in the field of human pluripotent cells in a small group setting. The workshop is organized in two parts : The first session is held in France (St-Raphael, Cote d’Azur), during which international experts will present the basics of stem cell biology as well as the most recent developments in the field. th Date : March 8-10 , 2009 The second session is an optional practical session which will take place in the United States (Farmington, Connecticut). Due to practical constraints, this session can accept only up to 8 participants who will be selected among participants of the first session. th Date : November 9-13 , 2009 The Workshop will be entirely held in English. It is a unique occasion to discuss Stem Cell Research in a small group setting with some of the world’s most outstanding specialists of the field.

Organizers: Pr Claire Rougeulle (UMR Epigénétique et Destin Cellulaire, Paris) Pr Marc Lalande (University of Connecticut, Farmington, USA)

Registration Fee First Session: St-Raphael, Cote d’Azur March 8-10th, 2009

Second session (8 participants max.) : Farmington, CT, USA November 9-13th, 2009

PIs and Researchers : 381,12 €

All participants : 609.80€ (121,96 €/day)

(PIs on the INSERM payroll : 289,65 €)

Research Engineers, Research Associates : 152,45 €

(PIs on the INSERM payroll : 381.10 €)

Technicians : 76,22 € Graduate students, post-docs, PhD students : 30,49 € Accomodation :

Accomodation (including lunch and dinner) for the First Session is provided on site at the St-Raphael Golf de l’Esterel Hotel at discounted fees : Single Room : 101,19 € / person / day Double Room : 68,08 € / person / day

The INSERM staff will be glad to assist you to registrate and organize your stay. Please don’t hesitate to contact them by e-mail or by phone : Armelle LE GOC Tel: +33.(0)1.44.23.62.04 Fax: +33.(0)1.44.23.62.93 Email: [email protected]

Where is the Workshop held ? The Workshop is held at the Latitudes - Golf De L'esterel Hotel Address of the Hotel :

How to get there :

Latitudes-Golf De L' Esterel-Hotel 805, Boulevard Darby 83700 Saint-Raphaël, France Tel : +33 8 25 88 68 45 Map:

Nearest Airport : Nice/Cote d’Azur Airport Then bus to St-Raphael

http://www.nice.aeroport.fr/

http://www.nice.aeroport.fr/upload/lignebus/7492331.pdf

From Paris : Direct High-Speed Train (4h45min) from Paris (Gare de Lyon) to St Raphael Railway Station

http://www.tgv-europe.com

Program

Inserm workshop # 192 “human pluripotent stem cells” March 8, 9 and 10, 2009, Saint Raphaël, France SUNDAY MARCH 8

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17:00 Welcome 17:15-19:30. Session 1: Epigenetic stability of hESC P.W. Andrews, Sheffield, UK; “Subsets of human ES cells: population dynamics, adaptation and cancer” V. Azuara, ICRF, UK; “Epigenetic signatures of stem-cell identity” L. Young, Nottingham, UK; “DNA methylation in human pluripotent cells” 19:30 DINNER MONDAY MARCH 9TH 9:00-11:45. Session 2: Derivation, manipulation and characterization of hESCs and iPS cells Frank Yates, Inserm U602, Villejuif; “Different reprogramming techniques to obtain induced pluripotent stem cells” J. De Vos, Inserm U847, Montpellier; "Understanding pluripotency to create pluripotency" A Murdoch, Newcastle UK; “Stem cells and the IVF clinic” 12:00-14:00. LUNCH 14:00-16:45 Session 3: Differentiation into different lineages, potential therapeutic applications Oliver Brüstle, Bonn; “From pluripotent stem cells to functional neurons and glia” Reubinoff BE, Hadassah University, Jerusalem; “Human Embryonic Stem Cells - Towards Future Therapy of Neurological Disorders” Anselme Perrier, Inserm U861/I-Stem, Evry; 17:30-19:00. Round table; Ethics and compliance Arnaud DeGuerra, Laure Coulombel, Agence de la Biomédecine 19:30. Cocktail 20:00. DINNER TUESDAY MARCH 10

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9:00-11:45. Session 4: Relationship to early human development, Part I Michel Pucéat, Inserm U861/I-Stem, Evry; “Le concept de niche dans l’autorenouvellement et la différenciation des cellules souches embryonnaires” C. Cowan, MGH/Harvard USA; "Twists of Fate: Programming and Reprogramming Development" L. Vallier, Cambridge, UK; “Mechanisms controlling early cell fate specification of pluripotent stem cells” 12:00-14:00. Lunch 14:00-16:00. Session 5: Relationship to early human development, Part II Lyle Armstrong, Newcastle UK; “Differentiation of pluripotent stem cells to germ cells” K. Eggan Harvard, USA; “Using stem cells and reprogramming to understand neural degeneration”

More information:

http://www.inserm.fr/fr/rh/ecole_inserm/ateliers/att00001612/Affichette192.pdf

Registration :

In English : Please contact Armelle LE GOC Tel: +33 1.44.23.62.04 Email: [email protected] French Registration Form (Registration deadline has been extended) http://www.inserm.fr/fr/rh/ecole_inserm/ateliers/att00001612/192FRPUB.doc