Program Exo Endo 2013 Thursday 4th of April 2013 1 3 : 3 0

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Session 1 Membrane trafficking in neurons

Chairs: S.Salinas / S.Gasman 1 6 : 0 0

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Session 2 Early steps in endocytosis

Chairs: D.Perrais/C.Lamaze –

Lunch Key note speaker Giampietro Schiavo O1

David Perrais

Lenkei Zsolt

Marine Laporte

O2

O3

O4

Coffee break Aurélien Roux

Philippe Chavrier

Cyril Basquin

Julie Mazzolini

O5

O6

O7

O8

Frederic Boal

Adrien Rousseau

Mahel Zeghouf

O9

O10

O11

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Session 3 Phosphoinositides and Membrane trafficking Chairs: B.Beaumelle/

Salle Camargue

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Welcome and Registration

Salle Camargue

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Salle Camargue

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H.Tronchere 1 9 : 3 0

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Dinner

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Poster Session 1 (salle Languedoc)

Friday 5th of April 2013 –

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Session 4 Membrane trafficking and pathogens I

Chairs: D.Muriaux/E.Kremer -

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Key note speaker Ari Helenius O12

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Cédric Delevoye

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Session 5 Recycling and late endocytic pathways

Chairs: G.Raposo/P.Chavrier 1 2 : 3 0

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Gaelle Boncompain O14

Philippe Benaroch O13

Christophe Chopard O15

Coffee break

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Salle 3 fontaines

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Breakfast Salle 3 fontaines

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O16

Guillaume van Niel O17

Jean-Baptiste Brault O18

Lunch Free time

Maximilian Fürthauer O19

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Session 6 Secretion mechanisms

Samuel Bouvet

El-Habib Hani

and the immune synapse

O20

O21

Ana-Maria Lennon-Duménil O22

Nathalie Sauvonnet O24

Eric Martinez

Oliver Nüsse

O25

O26

Chairs: F.Perez/N.Vitale 1 8 : 0 0

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Session 7 Membrane trafficking and pathogens II

Chairs: M.Bonazzi/C.Zurzolo 1 9 : 0 0

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Poster Session 2 (Salle plénière "les 3 fontaines")

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Gala Diner and Party

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Saturday 6th of April 2013 0 7 : 3 0 9 : 2 0

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Breakfast

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Annual Meeting Club Exo-Endo

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Session 8 Phagocytosis

and autophagy Chairs: F.Niedergand/ L.Espert 1 2 : 1 0 1 3 : 2 0

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Salle “les 3 fontaines”

AG

Coffee break

Key note speaker Felix Randow O27

Céline Jenzer

Aurélie Gueho

O28

O29

Lunch Departure

Maria-Isabel Thoulouze O23

Thursday 4

th

ORAL PRESENTATIONS Session 1 Membrane trafficking in neurons Chairs: Sara Salinas and Stéphane Gasman

14:20-15:00 Key note speaker: Giampietro Schiavo “Should I stay or should I go? Sorting decisions at the synapse for neurotrophins and pathogens” O1 15:00-15:20 David Perrais “Endocytosis and recycling of receptors in neuronal dendrites”. O2 15:20-15:40 Lenkei Zsolt “Cannabinoids induce actomyosin contractility leading to both rapid and lasting changes in neuronal morphology” O3 15:40-16:00 Marine Laporte “Characterization of Alix Knock Out mice phenotype : From brain disorders to cell morphology” O4

Session 2 Early steps in endocytosis Chairs: David Perrais and Christophe Lamaze 16:30-16:50 Aurélien Roux “Role of membrane elasticity in membrane endocytosis” O5 16:50-17:10 Philippe Chavrier “Identification of the metastasis suppressor, nucleoside diphosphate kinase NM23 as the GTP provider for dynamin in endocytosis” O6 17:10-17:30 Cyril Basquin “The WAVE complex is a new factor specifically involved in IL-2R endocytosis.” O7 17:30-17:50 Julie Mazzolini “Cellular trafficking and potential cytotoxicity of cerium oxide nanoparticles in lung derived cells” O8

Session 3 Phosphoinositides and membrane traffic Chairs: Helène Tronchère and Bruno Beaumelle

17:50-18:10 Frederic Boal “TOM1 (target of myb1 (chicken)) is a PI5P effector responsible for the EGFR degradation blockade in Shigella flexneri infected cells” O9 18:10-18:30 Adrien Rousseau “Phosphoinositide-mediated TRAF4 recruitment to tight junctions” O10

18:30-18:50 Mahel Zeghouf “Structure and membrane-controlled regulation of an endosomal ArfGEF involved in tumor invasion” O11 21:00-22:30 Poster Session 1

Friday 5th Session 4 Membrane trafficking and viruses Chairs : Delphine Muriaux and Eric Kremer 9:00-9:40 Key note speaker: Ari Helenius "Endocytosis in the service of viral pathogens" O12 9:40-10:00 Philippe Benaroch “A new targetable host factor is involved in the HIV-1 cycle in primary human macrophages” O13 10:00-10:20 Gaelle Boncompain “The anterograde trafficking of CCR5 as a therapeutic target for HIV infection” O14 10:20-10:40 Christophe Chopard “Palmitoylation of HIV-1 Tat regulates its capacity to inhibit neurosecretion and phagocytosis” O15

Session 5 Recycling and late endocytic pathways Chairs : Graça Raposo and Philippe Chavrier 11:10-11:30 Cédric Delevoye “BLOC-1 cooperates with KIF13A to extract endosomal tubules” O16 11:30-11:50 Guillaume van Niel “Characterization of amyloid associated structures at the surface of exosomes.” O17 11:50-12:10 Jean-Baptiste Brault “Rab11 is a novel regulator of BACE1 intracellular trafficking” O18 12:10-12:30 Maximilian Fürthauer “A dual role of the ESCRT complex in the function of ciliated organs in the Zebrafish.” O19

Session 6 Secretion mechanisms and the immune synapse Chairs : Franck Perez and Nicolas Vitale

16:40-17:00 Samuel Bouvet “Roles of the Arf1-GEF GBF1 in the remodeling of cellular membranes” O20 17:00:17:20 El-Habib Hani “A pool of type II alpha PKA is physically anchored to mature insulin secretory granules in pancreatic beta cells and is required for the functional coupling between the cAMP pathway and the potentiation of exocytosis” O21 17:20-17:40 Ana-Maria Lennon-Duménil “Front-back segregation of short-tail and long-tail class I Myosins regulates actin dynamics and the polarized trafficking of lysosomes to the B cell immune synapse” O22 17:40-18:00 Maria-Isabel Thoulouze “Tuba controls immune synapse dynamics and T cell activation” O23

Session 7 Membrane trafficking and pathogens Chairs : Matteo Bonazzi and Chiara Zurzolo 18:00-18:20 Nathalie Sauvonnet “Shigella effector IpaB-induced cholesterol relocation disrupts the Golgi complex and recycling network to inhibit host cell secretion” O24 18:20-18:40 Eric Martinez “High throughput screening of Coxiella burnetii virulence factors identifies an outer membrane protein involved in internalization” O25 18:40-19:00 Oliver Nüsse “The secret inner life of a phagosome” O26 19:00-20:30 Poster Session 2

Saturday 6th 9:20-10:20 Annual meeting Club Exocytose-Endocytose

Session 8 Phagocytosis and autophagy Chairs : Florence Niedergang and Lucile Espert 10:50-11:30 Key note speaker: Felix Randow " How cells defend their cytosol against bacterial invasion" O27

11:30-11:50 Céline Jenzer “Sequential roles of Atg8 homologs during autophagosome formation” O28 11:50-12:10 Aurélie Gueho “Characterisation of Mycobacterium marinum niches” O29