15th annual meeting
L’isle sur la sorgue 31st May-2nd June 2012 Thursday, May 31st 2012 11:00
Welcome and Registration
13:00- 14:30
Lunch
14:30 – 16:20
Session 1: Membrane trafficking and Neurological diseases Chairs : N. Vitale, R. Sadoul
14:30-15:00 15:00-15:20
15:20-15:40 15:40-16:00
Invited speaker: Frédéric Saudou (Paris, France) Axonal transport and energy supply Mohamed-Raafet Ammar (Strasbourg, France) The Coffin-Lowry syndrome-associated protein RSK2 regulates neuronal development through the phosphorylation of PLD1 and the synthesis of phosphatidic acid Sébastien Houy (Strasbourg, France) Oligophrenin-1: a molecular switch between exocytosis and endocytosis in neuroendocrine cells Karine Laulagnier (Grenoble, France) Study of the molecular regulation of the endo-lysosomal exocytosis pathway
16:00-16:20
Nadia Guettari (Sigma Aldrich) Zinc Finger Nucleases: a Novel Tool for Genome Engineering and Gene Function Analysis
16:20-16:45
Coffee break
16:45-17: 45
Session 2: Membrane trafficking and infection Chairs : F. Niedergang, N. Sauvonnet
16:45-17:05 17:05-17:25 17:25-17:45
Philippe Benaroch (Paris, France) A dynamic journey into HIV assembly in primary human macrophages Delphine Muriaux (Montpellier, France) A Rac1-derived signalling pathway is involved in HIV-1 Gag membrane localization, viral assembly and particle production in T cells Nicolas Boucherit (Marseille, France) Virulent Coxiella burnetii LPS avoids stimulation of the p38alpha-MAPK/HOPS axis to escape bactericidal phagolysosomes
17:45-18:45:
Session 3: Membrane trafficking and cancer Chairs : G. Raposo, C. Zurzolo
17:45-17:05 17:05-17:25 17:25-18:45
Guillaume Montagnac (Paris, France) Selective acetylation of microtubules at Clathrin-coated pits Chiara Recchi (London, UK) Rab27a controls MT1-MMP trafficking and tumour growth in vivo in breast cancer cells Pedro Monteiro (Paris, France) WASH and Exocyst complexes define a degradative mode of invadopodia of tumor cells through MT1-MMP endosomal exocytosis
20:00
Dinner
21:00-23:00
Poster Session 1
Friday, June 1st 2012 9:00-10:30
Session 4: Membrane fusion and fission Chairs: M. Seagar, D. Perrais
9:00-9:30 9:30-9:50 9:50-10:10 10:10-10:30
Invited speaker: Cesare Montecucco (Padova, Italy) Clostridial Neurotoxins and the Structure of the Neuroexocytosis Nanomachine Yann Desfougeres (Lausanne, Switzerland) Polyphosphate accumulation controls the size of the yeast vacuole via SNARE activation. Stéphanie Miserey-Lenkei (Paris, France) Rab, kinesin and acto-myosin dependent fission of transport vesicles at the Golgi complex Thierry Galli (Paris, France) A molecular network for the transport of the TI-VAMP/VAMP7 vesicles from cell center to periphery
10:30-11:00
Coffee break
11:00-12:50
Session 5: Membrane shaping and dynamics Chairs: S. Gasman, E. Coudrier
11:00-11:30 11:30-11:50 11:50-12:10 12:10-12:30
Invited speaker : Ludger Johannes (Paris, France) Glycosphingolipid-binding proteins in clathrin-independent endocytosis Jesus Ayala-Sanmartin (Paris, France) Basic cell penetrating peptides induce plasma membrane positive and negative curvature, lipid domain separation and protein redistribution. Christien Merrifield (Gif-sur-Yvette, France) A Feedback Loop between Dynamin and Actin Recruitment during ClathrinMediated Endocytosis Thibault Lagache (Paris, France) Computational imaging of clathrin-dependent and -independent endocytosis dynamics.
12:30-12:50
Sylvie Friant (Strasbourg, France) A tribute to the memory of our colleague Barbara Winsor who died on the 29th of September 2011.
12:50-14:00
Lunch
14:00 – 16:00 Free Time 16:00-16:45
Annual meeting du “Club Exo-Endo”
16:45-18:25
Session 6: Endolysosome dynamics Chairs: C. Hivroz, E. Gatti
16:45-17:05 17:05-17:25 17:25-17:45 17:45-18:05 18:05-18:25
Anne Reversat (Paris, France) Role of the CDC42/PAR polarity complex in antigen processing and presentation by B lymphocytes Ahmed Zahraoui (Paris, France) MICAL-like regulates EGFR endocytosis Emmanuelle Girard (Paris, France) Rab7 regulates early endosomal sorting. Ana-Joaquina Jimenez (Paris, France) A novel role for ESCRT-III proteins in plasma membrane repair. Derek McCusker (Bordeaux, France) Robust polarity establishment via and endocytosis-based cortical corralling mechanism
18:40-20:00
Drinks and Poster Session 2
20:00
Gala Dinner and Party
Saturday, June 2d 2012 9:30-11:00
Session 7: Membrane trafficking, development and cell division Chairs : Y. Bellaiche, R. Le Borgne
9:30-10:00 10:00-10:20 10:20-10.40 10:40-11.00
Invited speaker: M. Gonzalez-Gaitan (Geneva, Switzerland) Growth control by the Dpp morphogen Elizabeth Crowell (Paris, France) Cytokinesis abscission: what happens next? Véronique Proux (Paris, France) Role of the v-SNARE Cellubrevin/VAMP3 in epithelium formation Ariane Dimitrov (Paris, France) Myosotis, a new Golgi protein involved in cell cycle regulation.
11:00-11:20
Coffee break
11:20-12:40
Session 8: Organelles structures and dynamics Chairs : F. Perez, C. Lamaze
11:20-11:40 11:40-12:00 12:00-12.20 12:20-12.40
Fabien ALPY (Strasbourg, France) STARD3, a lipid transport protein involved in inter-organelle membrane contact sites formation Angela Cadou (Lausanne, Switzerland) Nucleus-Vacuole junctions in Saccharomyces cerevisiae: a role in lipid transfer between both organelles? Clémence Habourdin (Grenoble, France) Response to osmotic stress: a role for the endosomal arrestin-like protein AdcA? Sandrine Truchet (Jouy-en-Josas, France) SNARE proteins and milk products secretion
12:40-13:00
Closing Remarks
13:00-14:00
Lunch
14:30
Departure
