Philippe ATLAN

Expert C.V. Last modified on 25/04/2008

Printed on 2008-06-17 14:28:58 by ATLANP

Type of Expert FP6 Expert

No

FP7 Expert

Yes

Type of Expert

Evaluator/Reviewer

Non-FP Expert

Yes

Personal Details Candidature number

EX2006C135110

1. Title*

Dr.

2. Family name (current)* State your current family name, completely.

ATLAN

3. First name* State your principal first name, completely.

Philippe

4 . Sex *

male

5. Date of birth (YYYY-MM-DD)* Ex.: For 20 July 1957, write 1957-07-20.

1956-10-03

6. Town of birth*

Alger

7. Country of birth*

Algeria

8 . Nationality* The Commission will try to ensure a balanced participation with regard to geographical origin of applicants.

France

9. Passport number / Identity card number*

03VH43377

10. Second nationality if appropriate

Contact Details 11. Street number and name*

19, rue Pasteur

12. Town/city*

SCEAUX

13. Country *

France

14. Postal code

92330

15. PO BOX 16. Telephone number 1 *

33 6 07 84 1446

17. Telephone number 2 18. FAX number 1

33 6 07 84 14 46

19. FAX number 2

33 1 41 13 77 83

20. E-mail 1*

[email protected]

21. E-mail 2

[email protected]

22. TVA / VAT number

47928509000029

Linguistic Skills Languages

Written

Reading

Conversation

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23. Language 1: *

French

Mother Tongue

Mother Tongue

Mother Tongue

24. Language 2:

English

Good

Good

Fluent

25. Language 3:

Spanish

Elementary

Average

Elementary

FP Activities 26. FP6 Activity Codes 1.

2.

3.

4.

5.

6.

1. Health

2. Food, Agriculture, and Biotechnology

3. Investigator-driven resaerch

4. Industry-academia partnerships and pathways

5. Programme implementation and support to emerging needs

6. Research for the benefit of SMEs

27. FP7 Themes

Keywords 28. Please enter some Freestyle keywords that best describe your expertise (max 1000 characters) Health sciences - Medicine - Clinical pharmacology - Therapeutic nutrition - Gastroenterology - Intensive care - Nutrition related disorders - Geriatrics - Pediatrics - Pharmacy - Oncology - Business analysis - Innovation assistance - Market analysis - Innovation management - Industrial management - Research methodology - Food biotechnology - Biotechnology - Biomedical materials Pharmaceutical technology

Educational background 29. Diplomas 2005: University Diploma of Paediatric Obesity - University of Pierre and Marie Curie, Paris VI (France) 2004: University Diploma of medicine and surgery of Obesity - University of Pierre and Marie Curie, Paris VI (France) 1991: Master of Sciences (MSc) - Human Nutrition - Montreal University (Canada) 1989: Clinical & Research Fellowships in Padiatric Gastroenterology & Nutrition - Sainte-Justine Hospital, Montreal University (Canada) 1988: Master of Human Biology - Paris Sud University (France) 1988: Diploma of Bio Medical Statistics (CESAM) - Paris Sud University (France) 1987: EC Certificate of Specialization - Gastro-Enterology - Aix-Marseille University (France) 1986: Doctor of Medicine - Aix-Marseille University (France) 1984: University Diploma of Human Nutrition & Dietetics - University of Nancy (France)

Experience 30. Curriculum Vitae:

http://philoua.unblog.fr/curriculum-vitae/

33. Describe your experience if any in Peer Review, Evaluation/Validation, Impact Assessment, Monitoring, Quality Assurance or Auditing?: From scientific and business experience : . Scientific publications: authorship, submission and review . Clinical Research: conception, medical writing and review of protocols and reports related to internal and independant clinical studies : study protocols, ICH reports, internal product development plans, assessment and validation of submitted clinical programs for company granting; . Business development: opportunities assessment, due-diligences; . Medical marketing : conception, writing and review of market research surveys, questionnaires and reports.

Employment History 37. Are you currently employed or self-employed?*

yes

38. Current Organisation :

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Job Title:*

Founder, Associate

Organisation Name: *

Bio-MSI

Organisation Street Number and Name:* Organisation Town/City:*

19, rue Pasteur

Organisation Organisation Organisation Organisation

Country:* Postal Code: PO BOX: Type:*

SCEAUX France 92330 Consultancy firms

Organisation Size:*

1-9 employees

Department/Organisation Name:*

Bio-MSI

39. Employment Records for the last 10 years or the last 5 positions: * (max 2,000 characters) 09/05- 10/07 Director, Medical Marketing Europe, Medication Delivery, Division of Baxter Healthcare Medical Marketing and Business Development, (port-folio and therapeutic opportunities in the fields of Artificial Nutrition, Intensive Care, drug delivery devices for IV Therapies). 03 / 04 - 09/05 Director, Medical Marketing Europe, Bio-Pharma-Solutions, Business Unit of Medication Delivery division, Baxter Healthcare Medical Marketing, Clinical Development and Market Surveys, Generics and Drug delivery devices for IV Therapies 11/00 - 03/04 Director, Medical Development Global, Nutrition R&D, Baxter Healthcare • Medical Expertise for Baxter worldwide, in New Business Opportunities and Acquisitions in artificial nutrition ; • Medical Representative of Business Development Team and of Medical Advisory Board for Nutrition and Digestive Health 03/97- 11/00 Director, Medical Development Europe, Nutrition R&D, Baxter Healthcare • Management of Clinical Research activities • Development Project Leadership of Nutrition Products 01/95- 02/97 Associate Manager, Internal Medicine, Medical Development Direction, Synthelabo Group, • Clinical Research • Medical evaluation of new products • Development Strategy for OTC products • Company representative to the European Aspirin Foundation 09/92-12/94 International Project Leader, Synthelabo Research, • Clinical trials (Phase I - IV). • Gastro-Enterology, Hepatology, Allergology, Oncology, Migraine. 09/91-02/92 Medical Manager, Head of GI area products, Direction Médicale Groupe Delagrange Laboratories, • Research and Development of molecules in Gastro-Enterology, Clinical Positions Held 1992- 1997 Clinical activity: Centre d'Exploration Fonctionnelle Digestive, Paris • Part-time in a private health center, practice in adult and children functional

Interests 40 . Synopsis of current research interests: (max 1, 000 characters)* I am offering my support as consultant or medical partner to business projects and institutional programs in healthcare innovation- with special interest and skill in the links between health and nutrition and how these can be exploited to help prevent and even cure chronic diseases. Panel of offered services based on my knowledge and practical skills as a physician specialised in gastroenterology and nutrition with International clinical and research experience (France, Belgium, West Africa & Canada), as well as on 15-year long collaboration with the Pharma industry as Medical Director (Clinical research, medical marketing and Business Devlpt): . Operational and logistical support to SMEs involved in Biotechnology activities, . External support to Pharma and Food industries in their projects of innovative therapies and solutions, . Expertise in the assessment and monitoring of research projects for International Institutions in the management of their project calls.

41 . Former research interests (with dates): (max 1, 000 characters) - Paediatric malnutrition ( Senegal, 1983-1986) - Paediatric food hypersensitivity (Montreal, clnical and research fellowship 1986-1989) - Nutritional support in malabsorptive disorders (Brussels, 1990-1991) - Digestive motility disorders (Sanofi-Synthelabo, project leader, 1992-1995) - Pharmacological effects of food active ingredients (Baxter, Parenteral nutrition business, medical director, 1995-2007) - Clinical research (Sanofi-Synthelabo & Baxter, 1992-2003) - Drug pharmacology (Sanofi-Synthelabo & Baxter,1992-2003)

42. Additional Information: (max 10,000 characters) 1984 - 88 Member, Research & Study Group on Malnutrition 1986 - 91 Member, Canadian Society of Paediatrics 1991 & 1999 -2007 Member, European Society of Parenteral & Enteral Nutrition 1991 & 1999 - 2007 Member, French Society of Parenteral & Enteral Nutrition 1991 - 1997 Member, French Club of Digestive Motility 1996 - 1997 Member, European Aspirin Foundation (Synthelabo delegate)

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1997 - 2007 Association of Pharmaceutical Industry Physicians (AMIPS): Member 2000 - 2001 Executive Committee Affiliate Member 2000- 2001 European Federation of Pharmaceutical Industries and Associations (EFPIA- Brussels, Belgium) Pediatrics Task Force: Member (Baxter delegate) 2007- European Society of Intensive Care Medicine (ESICM) : Member

43 . Bibliography of Publications: ref. and title: (max 10,000 characters) UNIVERSITARY PUBLICATIONS 1. Atlan P Etude de bilans chez les enfants dénutris en cours de réhabilitation nutritionnelle. Comparaison avec des enfants sains vivant dans les mêmes conditions, en zône sub-urbaine de Dakar(Sénégal). Thèse de Doctorat en Médecine, Marseille, décembre 1986. 2. Atlan P Les entéropathies d’hypersensibilité alimentaire chez l’enfant : le diagnostic n’est pas facile. Mémoire de C.E.S. des maladies de l’Appareil Digestif, Marseille, décembre 1987. 3. Atlan P Etudes expérimentales pour l’établissement d’une méthode de diagnostic “in vitro” des allergies digestives chez l’enfant. Mémoire de Maîtrise en Sciences de Nutrition Humaine, juillet 1990, Université de Montréal, Montréal, Canada. Full publications and Chapters 4. Atlan P, Slavov R Vitamine A : apports et utilisation. Bulletin de l’OCCGE (Organisme de Coordination et de Coopération pour la lutte contre les Grandes Endémies, Afrique de l’Ouest), 1984, 94 :39-53. 5. Slavov R, Atlan P Physiologie de la vitamine A. Bulletin de l’OCCGE, 1984, 94 :25-38. 6. Seidman E, Sabbah S, Atlan P, Grey VL, Morin CL. Elemental diet in inflammatory bowel disease. Can J Gastroenterol 1988; 2:26-34. 7. Atlan Ph, Gurbindo C, Cousineau J, Lévesque D, Grey V, Levy E, Seidman E. The interaction of malnutrition and food allergy: in vitro studies using organ culture of intestinal biopsies. Proceedings of the 4th International G.E.R.M. Conference 1990. 8. Atlan Ph, Seidman E. Nutritional considerations in pediatric patients. Can J Gastroenterol 1990; 4:41-47. 9. Seidman EG, Atlan P, Roy CC. Enteral nutrition in inflammatory bowel disease. In: Inflammatory Bowel Diseases 1990. Rachmilewitz D and Zimmerman J (eds), Dordrecht, Kluwer Academic Publishers, 1990:141-158. 10. Carpentier YA, Atlan P Metabolism –Parenteral and Enteral Nutrition. Current Opinion in Anaesthesiology 1991, 4 : 253-256. 11. Poupon RE, Balkau B, Eschwege E & Poupon R (1991) A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. UDCA-PBC Study Group. N Engl J Med 324, 1548-1554. ( participation through the UDCA-PBC Study Group). 12. Delvaux M, Maisin JM, Arany Y, Atlan P, Prieto-Cabanis MJ, Canal M & Frexinos J (1995) The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther 9, 563-569. 13. Thomas-Gibson S, Jawhari A, Atlan P, Brun AL, Farthing M & Forbes A (2004) Safe and efficacious prolonged use of an olive oil-based lipid emulsion (ClinOleic) in chronic intestinal failure. Clin Nutr 23, 697-703. 14. Garcia De Lorenzo A, Denia R., Atlan P , Le Brun A, Evard D, Martinez Ratero S, Bereziat G, Fernandez Pavon A. Parenteral nutrition providing a restricted amount of linoleic acid in severely burned patients: a randomised double-blind study of an olive oil-based lipid emulsion v. medium/long-chain triacylglycerols. B. J. Nutr. 2005, 94: 221–230 15. Vahedi K, Atlan P., Bereziat G., Le Brun A., Evard D., Messing B A 3-month double-blind randomized study comparing an olive to a soybean oil-based intravenous lipid emulsion in home parenteral nutrition patients. B. J. Nutr. 2005, 94: 909-916 16. Cano NJM, Saingra Y, Dupuy Am, Portugal H, Lairon D, Cristol Jp, Come A, Le Brun A, Atlan P, Leverve Xm.Intradialytic parenteral nutrition: comparison of olive oil vs. soybean oil-based lipid emulsions. B. J. Nutr. 2006,95: 152-159. Abstracts, Oral Presentations and Posters 1. Seidman E, Lapointe N, Grey VL, Atlan P, Sabbah S, Duhaime A, Menezes J. Interleukin-2 (IL-2) production by peripheral mononuclear cells in children with IBD. Jerusalem, March 1987. Presented, Int. Symp. Immunol. of the Gastrointest. Tract and the Liver, 1987. 2. Seidman E, Lapointe N, Grey VL, Atlan P, Sabbah S, Duhaime a, Menezes J. Indomethacin-sensitive decreased interleukin-2 production by peripheral mononuclear cells in children with IBD. Gastroenterology 1987;92:1632. 3. Levy E, Roy CC, Bonin C, Gurbindo C, Thibault L, Letarte J, Sabbah S, Atlan P, Seidman E. Cyclosporin A induced lipid abnormalities in clinical and experimental conditions. Presented, AGA Conference, New Orleans, LA, May 1988. Gastroenterology 1988; 94:A260.

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4. Gurbindo C, Atlan P, Chad Z, Morin C, Duhaime A, Seidman E. Lymphocyte responses to specific dietary antigens in food intolerance reactions. Gastroenterology 1988;94:A162. 5. Gurbindo C, Chad Z, Atlan P, Sabbah S, Morin C, Duhaime A, Seidman E. Lymphocyte responses to dietary antigens in eosinophilic gastroenteropathy and milk protein intolerance. Presented, 11th International Convocation on Immunology. Buffalo, New York, June 1988. 6. Gurbindo C, Levy E, Sabbah S, Atlan P, Duhaime A, Seidman E. Lymphocyte function in Cyclosporin treated rats. Presented, 11th International Convocation on Immunology. Buffalo, New York, June 1988. 7. Atlan P, Seidman E, Gurbindo C, Levy E, Grey V, Cousineau J, Caya S, Morin C. Organ culture studies of small intestinal biopsies in cow's milk intolerance. Presented, Annual Conference, North American Society for Pediatric Gastroenterology, Chicago, November 1988. 8. Atlan Ph, Gurbindo C, Cousineau J, Grey V, Levy E, Seidman E. Interaction de la mal¬nutrition et de l'hypersensibilité alimentaire: Etude "in vitro" par la culture organotypique d'explants intestinaux murins. Presented, 4ièmes Journées Scientifiques Internationales du Groupe de Recherche et d'Etudes sur la Malnutrition. Spa, Belgium, avril 1989. 9. Atlan P, Manzanares J, Gurbindo C, Roy C, Pelletier L, Chad Z, Seidman E. Evaluation of predictors of primary vs secondary hypogammaglobulinemia in pediatric patients with protein-losing enteropathy. Ped Res 1989; 25:107A. 10. Atlan Ph, Gurbindo C, Levy E, Grey V, Seidman E. In vitro diagnosis of milk protein enteropathy using intestinal organ cultures. Presented, American Gastroenterological Association, Washington, DC, May 1989. Gastroenterology 1989; 96:A16. 11. Seidman E, Atlan Ph, Morin C. Traitement nutritionnel du retard de croissance associé aux maladies inflammatoires chroniques de l'intestin chez l'enfant. Presented, Congrès Mondial de la Pédiatrie. Paris, juillet 1989. 12. Atlan Ph, Gurbindo C, Levy E, Grey V, Morin C, Seidman E. Diagnostic des entéropathies aux protéines bovines par culture organotypique de l'intestin. Presented, Congrès Mondial de la Pédiatrie. Paris, juillet 1989. 13. Atlan Ph, Manzanares J, Gurbindo C, Roy C, Pelletier L, Chad Z, Seidman E. Paramètres simples distinguant les hypogammaglobulinémies primaires et secondaires chez des enfants avec entéropathie exsudative. Presented, Congrès Mondial de la Pédiatrie. Paris, juillet 1989. 14. Gurbindo C, Poullain M, Grey VL, Atlan P, Duhaime A, Seidman E. IL-1 inhibits proliferation of a murine intestinal epithelial cell line. Presented, 3rd International Symposium on Inflammatory Bowel Diseases, Jerusalem, September 1989. 15. Gurbindo C, Sabbah S, Atlan Ph, Levesque D, Seidman E. Interleukin-2 production by rat lamina propria lymphocytes in experimental colitis. Presented, 3rd Annual Conference, North American Society for Pediatr. Gastroenterol. and Nutr. Chicago, October 1989. 16. Atlan Ph, Gurbindo C, Cousineau J, Grey V, Levy E, Seidman E. The effect of malnutrition on food antigen induced enteropathy in the mouse. Presented, 3rd Annual Conference, North American Society for Pediatric Gastroenterology and Nutrition. Chicago, October 1989. 17. Atlan Ph, Gurbindo C, Seidman E. Diagnostic des entéropathies aux protéines bovines par culture organotypique de l'intestin. Presented, XXIe Réunion Annuelle du Club de Recherches Cliniques du Québec, Ste-Adèle, Octobre 1989. 18. Lacaille F, Gurbindo C, Atlan P, Duhaime A, Seidman E. Eosinophilic colitis in infants with cow's milk sensitivity. Presented, American Gastroenterological Association, San Antonio, Texas, May 1990. Gastroenterology 1990;98:A419. 19. Gurbindo C, Agulnik J, Atlan P, Duhaime A, Seidman E. Interleukin-2 enhances thymidine incorporation by a murine crypt intestinal cell line. Presented, American Gastro¬enterological Association, San Antonio, Texas, May 1990. Gastroenterology 1990;98:A413. 20. Justinich C, Katz A, Gurbindo C, Atlan P, Bouthillier L, Seidman E. Elemental diet therapy reverses the enteropathy and growth failure associated with severe eosinophilic gastroenteritis. Presented, American Gastroenterological Association, San Antonio, Texas, May 1990. Gastroenterology 1990;98:A66. 21. Gurbindo C, Mansour AM, Atlan P, Seidman E. Tumor necrosis factor-a stimulates intestinal epithelial cell line (IEC-6) proliferation. Presented, 3rd Annual Gastroenteric Biology Conference, Chicago, October 1990. 22. Atlan P, Gurbindo C, Seidman E. In vitro intestinal cell proliferation and differentiation are affected by malnutrition in the mouse. Presented, 3rd Annual Gastroenteric Biology Conference, Chicago, October 1990. 23. Bianchetti G, Molinier P, Atlan P, Morselli PL. Pharmacocinetic interaction between Aspegic ( acetylsalicylate of lysine) and Primperan ( metoclopramide) in young healthy volunteers. Vth European Congress of Biopharmaceutics and pharmacokinetics. 24. Delvaux M, Maisin JM, Arany Y, Atlan Ph, Cabanis MJ, Canal M, Frexinos J Effects of the 5-TH3 Antagonxit/5 HT-4 agonist lintopride on esophageal motility. A dose-response study in healthy volunteers. Gastroenterology, 102 ; 1993. 25. Delvaux M, Maisin JM, Arany Y, Atlan Ph, Cabanis MJ, Canal M, Frexinos J Effet du lintopride sur la motricité oesophagienne. Etude Dose-effet chez le volontaire sain. Gastr. Clin. Biol. March 1993.

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26. Cargill G, Atlan P, Tudor D et al. Association of Helicobacter pylori and reflux esophagitis in symptomatic children. Gastroenterology 1996; 106: A59-9. 27. Cano N., Saingra Y., Portugal H., Lairon D., Cristol J.P., Come A., Le Brun A., Atlan P., Leverve X., Lerebours E. Nutrition parentérale perdialytique (NPPD) : comparaison de deux émulsions lipidiques à base d’huile d’olive ou de soja. 21ème S

44. Authorise Member States and the States associated to the framework programmes to access the data submitted by you? *

yes

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