1er Colloque Annuel du CSB - Lundi 17 Juin 2019 1st Annual CSB Symposium - Monday, June 17, 2019 8h00

Ouverture du Bureau d’Inscription / Registration Desk Opens Entrée Salle de Bal / Ballroom Lobby

8h00-9h00

Installation des Affiches / Poster Set-up Café & Croissants avec les Exposants / Coffee & Croissants with Exhibitors Salle de Bal / Ballroom

9h00-9h15

Mots d’Ouverture / Opening Words – Alba Guarné, McGill University and Associate Director of CSB

Salle de Bal / Ballroom A

Séance 1 / Session 1

Sous la Présidence de / Session Chair: Alba Guarné, McGill University 9h15-10h00

Lorena Beese, Duke University Medical Center Miraculous machines: inner workings of human DNA mismatch repair

10h05-10h25

Laurent Cappadocia, Université du Québec à Montréal Structural and functional characterization of SUMO E3 ligases

10h30-10h40

Matthias Langhorst, CMO, Refeyn Ltd Weighing molecules with light – a new way to study biomolecules

10h45-11h15

Pause Santé avec les Exposants / Health Break with Exhibitors

Salle de Bal / Ballroom A

Séance 2 / Session 2

Sous la Présidence de / Session Chair: John Pascal, Université de Montréal 11h15-11h35

Javier Vargas, McGill University Computational strategies to process highly heterogeneous cryoEM samples

11h40-12h00

Charles Calmettes, INRS-Armand Frappier Structures of the cGMP-dependent protein kinase in malaria parasites reveal a novel structural relay mechanism for activation

12h05-12h15

Stefano Rubino, Soquelec Improving throughput for cryo-electron microscopy

12h20-13h30

Diner (Buffet avec les Exposants) / Lunch (Buffet Style with Exhibitors)

Salle de Bal / Ballroom A

Séance 3 / Session 3

Sous la Présidence de / Session Chair: Joaquin Ortega, McGill University 13h30-14h15

Dmitry Lyumkis, The Salk Institute for Biological Sciences Beyond the resolution revolution: mapping the ribosome assembly landscape using single particle cryo-EM

14h20-14h40

Jyh-Yeuan (Eric) Lee, University of Ottawa ABC transporter: cholesterol and beyond

14h45-15h00

Pause / Break

Salle de Bal / Ballroom A

Séance 4 / Session 4

Sous la Présidence de / Session Chair: Camille Fortinez, McGill University 15h00-15h12

Ryan Killoran, IRIC / Université de Montréal Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel

15h15-15h27

Roman Sarrazin-Gendron, McGill University Efficient prediction of recurrent local 3D structure networks in RNA sequences

15h30-15h42

Amal Seffouh, McGill University RbgA triggers folding of the 50S subunit functional sites

15h45-15h57

Yann Ayotte, INRS-Armand Frappier Discovering quality drug seeds by practical NMR-based fragment screening

16h00-16h12

Meng Yang, McGill University Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements

Salle du Parc / du Parc Room

Séance 5 / Session 5

Sous la Présidence de / Session Chair: Shreya Krishnan, McGill University 15h00-15h12

Yao Shen, McGill University The heptameric assembly of TnsC bound to DNA reveals the activation mechanism of TN7 transposition

15h15-15h27

Élise Rouleau-Turcotte, Université de Montréal Structural basis of the allosteric communication in human poly(ADP-ribose) polymerase 1, 2 and 3

15h30-15h42

Leah Pollet, McGill University Bioinformatics analysis of the evolution of protein-protein interactions

15h45-15h57

Ngoc Thu Hang Pham, INRS-Armand Frappier Homodimer interface mutations of human galectin-7 alter its biological activity

16h00-16h12

Shafqat Rasool, McGill University PINK1 activation and substrate phosphorylation

Salle de Bal / Ballroom A and B 16h15-18h15

Séance 6 / Session 6

Salon des Affiches & Salon des Exposants / Poster Pub & Exhibition Area Open Présentation des Prix & Remerciements / Presentation of Awards & Closing Words