MATILDE CORDERO-ERAUSQUIN - CURRICULUM VITAE IDENTIFICATION Name:
Matilde Cordero-Erausquin
Office:
Institut des Neurosciences Cellulaires et Intégratives, CNRS UPR 3212 Département Nociception & Douleur 21, rue René Descartes 67084 Strasbourg cedex, France
Telephone: Fax:
+33 3 68 85 14 68 +33 3 88 61 33 47
Email :
[email protected]
Citizenship:
French and Argentinean
EDUCATION / TRAINING 2012
HDR, Strasbourg University
2006-2007
Post-doctoral fellow, McGill University, Montreal Supervisor: A. Ribeiro-da-Silva
2003-2006
Post-doctoral fellow, Université Laval, Québec. Supervisor: Y. De Koninck
2003
PhD, Molecular and Cellular Pharmacology, University of Paris 6 (with distinction) Supervisor: J.-P. Changeux Title: Molecular and cellular study of acetylcholine nicotinic receptors in aminergic and pain pathways.
1998
M.Sc., Ecole Normale Supérieure Paris-Ulm (with distinction, rank: 2 )
nd
APPOINTMENTS Since 2013
Young Investigator at the European Neuroscience Institute at Strasbourg (ENINET)
Since 2011
CNRS tenured Researcher (CR1), INCI CNRS UPR3212, Strasbourg, France
2007-2011
CNRS junior Researcher (CR2), Strasbourg, France.
DISTINCTIONS AND AWARDS 2013-2015
Fellow
University of Strasbourg Institute of Advanced Studies (USIAS)
2006-2008
Fellowship
Canadian Institutes of Health Research Post-doctoral fellowship Ranked 2nd / 322, 4th/503 nationally.
2005
Award
French Ministry of Post-graduate Studies and Research “Initiative Post doc”, Program in support for the return of French postdoctoral fellows.
2004
Award
Canadian Institutes of Health Research IALA / IMHA Best Poster Award « For excellence in unraveling the mechanisms underlying pain and nociception» (Membrane Proteins In Nociception And Pain, Montreal) 1/5
2003-2006
Fellowship
Fonds de la recherche en santé du Québec Post-doctoral fellowship
1998-2002
Fellowship
French Ministry of Post-graduate Studies and Research PhD fellowship
1995-1998
Scholarship
French Ministry of Post-graduate Studies and Research Bachelor and Master scholarship (Ecole Normale Supérieure)
Travel Awards: 2010
Bioseb Inc. & Réseau Québécois de Recherche sur la Douleur Satellite Symposium Francophonie-Douleur, Sherbrooke & Satellite Symposium "Imaging Pain: From cells to Brains", Québec
2005
International Association for the Study of Pain (Financial Aid Grant) 11th World Congress on Pain, Sydney, Australia
2002
Women In Neuroscience (WIN) Travel Award Aide aux congrès internationaux, Ministère des Affaires Étrangères, France Society for Neuroscience Annual Meeting, Orlando, USA
2001
Marine Biological Association (UK) Workshop on Microelectrode Techniques for Cell Physiology, Plymouth, UK
2000
Instituto Juan March (Madrid) The molecules of pain : molecular approaches to pain research, Madrid, Spain
1999
International Society of Neurochemestry Neuronal nicotinic receptors: from structure to therapeutics, Venice, Italy
TEACHING EXPERIENCE Since 2008
“Electronics applied to patch-clamp”, Electrophysiology School of Strasbourg
Since 2007
“Pain and the autonomous system”, Neuroscience Master course, Strasbourg University
2004-2006
Physiology Bachelor examination, Laval University, Québec
2002-2003
Teaching Assistant (Attaché temporaire d’enseignement et de recherche), Collège de France, Paris, France
1999-2002
Teaching Assistant (Allocataire Moniteur Normalien), University of Paris 6, France
SUPERVISION OF TRAINEES Post-doctoral fellow Name Maria Carmen Medrano Sophie Pawlowski
Degree Post-doc Post-doc
Project In vivo recording of cholinergic interneurons ChAT interneurons in the monkey dorsal horn
University
Period
Strasbourg
2014-
Strasbourg
2012
Current position
Post-doc at McGill
2/5
Graduate students Name Sehrazat Kavraal Dhanasak Dhanasobhon Dhanasak Dhanasobhon
Degree PhD PhD. Trinational M. Sc.
Bruce Mesnage
PhD
Vivien Zell
M. Sc.
Matthieu Hammer Tiphaine Dolique
Project Temporal cholinergic modulation of neuronal circuits Chronic pain and the spinal cholinergic system Behavioral analysis of the spinal cholinergic tone The cholinergic system and the modulation of spinal nociceptive transmission Recording of dorsal horn cholinergic neurons in cultures Characterization of ChAT::EGFP mice
University Strasbourg / Amsterdam Strasbourg Strasbourg / Basel / Freiburg Strasbourg, European Doctoral College
Period Started in 2014 Started in 2013 20122013
Current position (expected end in July 2017) (expected end in July 2016)
20092013
Graduated in November 2013
PhD student
PhD student in Luxembourg PhD student in Göttingen
Strasbourg
2009
Strasbourg
2008
Transynaptic tracing
Paris /Laval
2006
Post-doc at McGill
Degree
Project
University
Period
B. Sc.
Stereological injections
Laval University
2005
Current position PhD student at Laval
M. Sc. M. Sc.
Undergraduate research trainee Name Guillaume Lavertu
OTHER CONTRIBUTIONS AND RESPONSABILITIES Ad hoc Reviews: Neuropharmacology, Molecular Pain, Experimental Brain Research, European Journal of Pain Thesis committee: 2013 Vladimir Farar
Neuroscience, University of Paris 6, & Charles University, Prague
Graduate student advisory committee: 2012 Joseph Chaumont Neuroscience, Strasbourg University
Sup.: Dr. E. Krejci & Dr. J. Myslivicek Sup.: Dr. P. Isope
Administrative committee: Since 2009 Seminar Series committee Profession societies: International Association for the Study of Pain, Société française des Neurosciences INVITED LECTURES th
15 World Congress on Pain, Buenos Aires, Argentina (2014) th
14 World Congress on Pain, Milano, Italy (2012) 7eme Symposium du Réseau National de Recherche sur la Douleur, Versailles, France (2011) Satellite Symposium Francophonie-Douleur, Sherbrooke, Québec (2010) Wake Forest University, Winston-Salem, USA (2007) Ecole Normale Supérieure, Paris, France (2006) Canadian Physiological Society Winter Meeting, Mont Ste-Anne, Canada (2005) ABCDouleur annual meeting, Montréal, Canada (2005) 3/5
European Colloquium on Pain, Grugliasco-Torino, Italy (2003) University of Chicago, Illinois, USA (2003) Université Laval – Robert Giffard, Québec, Canada (2002) Vollum Institute – Oregon Health Science University, Portland, USA (2002)
PUBLICATIONS The names of trainees I have supervised are underlined. 11.
Pawlowski S.A., Gaillard S., Ghorayeb I., Ribeiro-da-Silva A., Schlichter R. and Cordero-Erausquin M. (2013), A novel population of cholinergic neurons in the macaque spinal dorsal horn of potential clinical relevance for pain therapy. J. Neurosci. 33(9):3727-37
10.
Mesnage B., Gaillard S., Godin A., Rodeau J.L., Hammer M., von Engelhardt J., Wiseman P., De Koninck Y., Schlichter R. and Cordero-Erausquin M. (2011), Morphological and functional characterization of cholinergic interneurons of the dorsal horn of the mouse spinal cord. J. Comp. Neurol. 519(16):3139-58
9.
Yalcin I, Charlet A., Cordero-Erausquin M., Tessier L.H., Picciotto M., Schlichter R., Poisbeau P., Freund-Mercier M.J., Barrot M. (2011), Spinal β2-subunit-containing nicotinic acetylcholine receptors are critical for the control of nociceptive thresholds in mice. Pain 152(9):2131-7
8.
Cordero-Erausquin, M., Allard, S., Dolique, T., Bachand, K., Ribeiro-da-Silva, A. and De Koninck, Y. (2009) Dorsal horn neurons presynaptic to lamina I spino-parabrachial neurons revealed by transynaptic labelling. J. Comp. Neurol. 517(5):601-15.
7.
Cordero-Erausquin M., Coull J.A.M., Boudreau D., Rolland M. and De Koninck Y. (2005) Differential maturation of GABA action and anion reversal potential in spinal lamina I neurons: impact of chloride extrusion capacity. J. Neurosci. 25: 9613-9623
6.
Cordero-Erausquin M., Pons S., Faure Ph. and Changeux J.P. (2004) Nicotine differentially activates inhibitory interneurons and projection neurons in the spinal cord. Pain 109: 308-318
5.
Champtiaux, N., Gotti, C., Cordero-Erausquin, M., David, D.J., Przybylski, C., Léna, C., Le Novère, N., Arroyo-Jimenez, M.D., Clementi, F., Moretti, M., Rossi, F.M., McIntosh, J.M., Gardier, A.M. and Changeux, J.P. (2003) Function and subunit composition of nicotinic receptors in dopaminergic neurons investigated with knockout mice. J. Neurosci. 23:7820-7829
4.
Cordero-Erausquin, M. and Changeux, J.P. (2001) Tonic nicotinic modulation of serotoninergic transmission in the spinal cord. PNAS 98:2803-2807.
3.
Cordero-Erausquin M., Marubio L.M., Klink K., Changeux J.P. (2000) Nicotinic receptor function : new perspectives from knockout mice. Trends Pharmacol. Sci. 21 : 211-217
2.
Marubio, L.M., Arroyo-Jimenez, M.M., Cordero-Erausquin, M., Léna, C., Le Novère, N., Huchet, M., Damaj, M.I. and Changeux, J.P. (1999) Reduced antinociception in mice lacking neuronal nicotinic receptor subunits. Nature 398:805-810
1.
Lena C., d'Exaerde A.D., Cordero-Erausquin M., Le Novere N., Arroyo-Jimenez M.D. and Changeux J.P. (1999) Diversity and distribution of nicotinic acetylcholine receptors in the locus ceruleus neurons. PNAS 96 (21) : 12126-12131
Other publications: 2.
Isope P. and Cordero-Erausquin M. (2011) La révolution optogénétique dans la biologie moderne. La lettre des neurosciences N°40:17-19 (Bulletin de la Société des Neurosciences)
1.
Cordero-Erausquin M. (2011) Les interneurones cholinergiques spinaux : clé de voûte de l’analgésie cholinergique. Douleur et Analgésie 24:S34-35 4/5
Career Summary (Source: ISI Web of Knowledge): Peer-reviewed publications: Citations to date: Average:
11 1081 72 citations per year
FUNDING Current: Funding agency and program
Principal Investigator
Funding period
Amount
Alsace Region (PhD fellowship for Dhanasak Dhanasobhon)
Cordero-Erausquin
2015-2016
43 650 €
ANR (French National Research Agency) Jeunes Chercheuses et Jeunes Chercheurs
Cordero-Erausquin
2014-2017
291 928 €
USIAS fellow (University of Strasbourg Institute of Advanced Studies)
Cordero-Erausquin
2013-1015
200 000 €
Projet International de Coopération Scientifique (CNRS)
Cordero-Erausquin
2013-2015
21 000 €
FRM (Fondation pour la Recherche Médicale) PhD fellowship for Bruce Mesnage
Cordero-Erausquin
2012-2013
31 200 €
FRM (Fondation pour la Recherche Médicale) Support to new research themes
Cordero-Erausquin
2011-2013
6 000 €
Samuel de Champlain (Commission permanente de coopération franco-québécoise)
Cordero-Erausquin De Koninck
2011-2013
28 500 €
Funding agency and program
Principal Investigator
Funding period
Amount
Alsace Region (PhD fellowship for Bruce Mesnage)
Cordero-Erausquin
2011-2012
36 375 €
IFR (Neuroscience federative institute, Strasbourg) Developing optogenetic tools
Isope
2011
15 000 €
IASP (International Association for the Study of Pain) Early Career Research Grant
Cordero-Erausquin
2010-2011
20 000 US$
Strasbourg University Scientific Council
Cordero-Erausquin
2008
20 000 €
INCI Scientific Council
Cordero-Erausquin
2008
5 000 €
Past:
CAREER INTERRUPTIONS Maternity leaves 01→09/2009 and 06/2012→01/2013 (both leaves include a preventive withdrawal because of high risk of premature delivery)
5/5
