Recognition of interim FDG PET as a potential surrogate for
Subjectivity is the Achilles heel of visual iPET reading; many published iPET results lacked consistent/std criteria. â« To fulfill this need, a graded method of visual ...
I never think of the future, it comes soon enough.
Disease-based
A Einstein
Individualized
Recognition of interim FDG PET as a potential surrogate for chemosensitivity laid groundwork for response-adapted therapy trials
Risk-adapted
Response-adapted ?
Subjectivity is the Achilles heel of visual iPET reading; many published iPET results lacked consistent/std criteria To fulfill this need, a graded method of visual criteria were proposed at an international meeting held in Deauville, 2009 Meignan M, Leuk Lymphoma. 2009;50:1257 Deauville 5-point scale
• Two independent international validation studies (IVS) launched to validate the proposed 5-p scale to establishre producibility and the predictive role of interim PET in HL and DLBCL • Role of SUVs were also investigated in the DLBCL study Itti E, J Nucl Med. 2009;50:527
Deauville Criteria for the Assessment of Interim PET in Advanced Stage Hodgkin Lymphoma Patients Enrolled in the International Validation Study Study. A Gallamini, et al International Validation Study of the Deauville Criteria for Interim FDG PET/CT Interpretation in Diffuse Large B-Cell Lymphoma. E Itti, et al
Pressing Questions (imaging community) 1. Are we ready to introduce the routine clinical use of interim PET and Deauville 5-PS interpretation criteria for HL ?
2. Are we ready to introduce the routine clinical use of interim PET and Deauville 5-PS interpretation criteria for DLBCL ?
Pressing Questions (clinicians) 1. Was the predictive value of interim PET confirmed by the IVS study with sufficiently robust data in HL patients ?
2. Was the predictive value of interim PET confirmed by the IVS study with sufficiently robust data in DLBCL patients?
Prospective, biopsy controlled determination of. âpositive PETâ. â¢. Therapy interval 2 weeks. â¢. PET 10-14 days post cycle 4. â¢. Treatment is adapted by biopsy,.
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after 2 cycles of chemotherapy in Diffuse Large B-cell. Non-Hodgkin's Lymphoma. Short title: PET after 2 cycles. A sub-study of the R-CHOP-21 v R-CHOP-14 ...
if + (scores 4-5) or equivocal (score 3) then PET after 2 ABVD cycle. ⢠N=199 HL. 54 I-IIA .... Baseline MTV predictive of PFS and OS although tumor bulk was not.
R.O. Casasnovas*, M. Meignan, A. Berriolo-Riedinger, S. Bardet, A. Julian, C. Thieblemont,. P. Vera, S. Bologna, J. Brière, J.P. Jais, C. Haioun, B. Coiffier and F.
Sep 25, 2011 - lymphoma, new radiotracers and new imaging modalities. ⢠Evolving drugs: the era of targeted therapy could change the way we use PET ...
Oct 5, 2012 - S Bardet, E Itti, C Kobe, S Muller,. S Barrington, A Biggi, L Kostakoglu. A Gallamini, M.Meignan,. Chair: C Haioun, A Engert. Alberto Biggi.
Fast upload of the images and anonymization. All PET/CT volume files and not just « selected images ». Non attenuation and attenuation corrected images ...
after 2 cycles of chemotherapy in Diffuse Large B-cell. Non-Hodgkin's Lymphoma. Short title: PET after 2 cycles. A sub-study of the R-CHOP-21 v R-CHOP-14 ...
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Predictive value of interim PET. Focus on ... X. Kostakoglu. J Nucl Med 2002. 30 ... Curability. PET is more than just an image ... Which level ( 4/5, âSUV value)?.
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Apr 8, 2010 - PET Imaging Centre, Nuclear Medicine Department, Santa Croce Hospital â Cuneo â Italy. S. Chauvie ... Therapy: ABVD x 6 cycles with/without consolidation radiotherapy. - Staging at ... PATIENTS WITH MISSING DATA: 14.