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April 10-11-12, 2002
3 rd Deauville international Conference on
spinal cord injury
programme
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Welcome to Deauville A L A I N P R I VAT
President of the Conference
This third edition of the Deauville meeting, on spinal cord injury – the first of the third millenium – is marked by the emergence in this field of new technologies: stem cells, transgenics, which provide new tools for basic research.
of innovative therapeutic strategies based on the one hand on more refined molecular and cellular analyses of pathophysiologi cal phenomena, and on the other hand on more appropriate and more predictive pre-clinical models.
In addition, the progress of imaging techniques, such as MRI, which can now be applied to small mammals, and which has acquired a functional dimension, are beginning to bridge the gap in between preclinical studies on laboratory mammals and clinical observations in humans.
The increasing number of research teams involved in this endeavour is a good omen. It is thus more necessary than ever that the best level of communication develops in between basic scientists and clinicians. This is the purpose and the expectation of this meeting.
It is expected that this first decade of the 21st century will witness the development
Invited speakers J.Y. Barthe (France), F. Clarac (France), O. Danos (France), S. Dumas (France), R. Edgerton (USA), M. Filbin (USA), H.D. Fournier (France), P. Gauthier (France), M. Gaviria (France), F. Giuliano (France), M. Gimenez y Ribotta (France), D. Green (USA),
Committees
Ch. Henderson (France), J. Hounsgaard (Denmark), J.F. Julien (Canada), M. Keith (USA), Ph. Lanièce (France), S. Lumbroso (France), R. McKay (USA), V. Meininger (France), J. Melki (France), R.W. Oppenheim (USA), D. Price (USA), R.M. Quencer (USA), M. Nieto Sampedro (Spain),
Organization Committee
Posters are most welcome and will be displayed for the duration of the Symposium. Two prizes of 700 and 400 will be respectively attributed to the two best posters whose first author is under 35 years.
Committees
Scientific Committee
President :
Alain PRIVAT
President :
Members :
Patrick CHOAY
Members :
Jacques CONS
D. Strosberg (France), M.Tadié (France), R.Turner (U.K), A.Wagner (France), J.Wasserberg ( U.K.), A.Wernig (Germany)
Jacques MALLET, PhD
Paul DOLLFUS,MD Michel HAMON,PhD
Paul DOLLFUS
Didier ORSAL,PhD
Gabriel MAILLARD
Brigitte PERROUIN-VERBE,MD
Jacques MALLET
Alain PRIVAT, MD, PhD
Françoise POZZO di BORGO
Charles TATOR,MD
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instructions Deadlines Reception of abstracts : Early registration fee : (after that date, full registration fee)
December 15, 2001 before December 31 st 2001
Accomodation reservation : (no guarantee can be given after that date)
before April 2, 2002
Language The official language of the symposium will be English.
Posters Oral communications are only invited but posters are most welcome and should concern one or more of the covered topics.They will be displayed for the duration of the Symposium. One hour daily is reser ved for the posters.There will be no discussion session.Two prizes of 700 and 400 will be respectively attributed to the two best posters whose first author is under 35 years.
Posters abstract submission For writing and presentation, please keep the guidelines of the attached abstract form model.The closing date for the posters abstracts to be examined for acceptance by the Scientific Committee is December 15, 2001 (post stamp). Along with notification of acceptance, authors will receive all technical information regarding poster preparation.
Addresses Information and registration
Institut pour la Recherche sur la Moelle Epinière (IRME) Conference Secretariat 45, rue Vineuse F - 75116 Paris - France Phone :+33 1 44 05 15 43 Fax.+33 1 44 05 15 22 e-mail :
[email protected] www.irme.org
Publications The abstracts of the presentations and posters will be published in English in the book of the symposium.
Hotel reservation : Sophie Bréard Booth reservation : Sandrine Mengeot
Commercial exhibition
Centre International de Deauville (C.I.D.)
An exhibition of medical and laboratory instruments and pharmaceuticals will take place in the CID. It will be opened on Wednesday April 10,Thursday April 11 and Friday April 12 from 8.30 to 18.30. Equipped booth (9m 2) : for information, please contact CID. Welcoming reception, coffee breaks and lunches will be offered to the exhibitors, for the duration of the congress.
BP 171 F - 14800 Deauville Phone :+33 2 31 14 14 14 Fax.+33 2 31 14 15 16 e-mail :
[email protected] www.congres-deauville.com
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6 sessions of half a day each
The meeting schedule 1 2 3 4 5 6
Posters will be displayed for all the duration of the meeting
Physiology and Physiopathology of Spinal Cord Regeneration Motoneuron diseases Emerging Technologies Imaging Clinical Research
Tuesday April 9 Evening 20.00-21.00 Welcoming reception
Wednesday April 10 Morning 1 Physiology and Physiopathology of Spinal Cord Chairperson F. CLARAC, France 08.00 08.30 09.00 10.00 10.30 11.00 11.30 12.00 12.30 13.00
Welcome Opening Ceremony Physiopathological mechanisms of spinal locomotion in animal models Intrinsic response properties of spinal motoneurons regulated by metabotropic receptors Coffee Break Comparative data on locomotor generator in the spinal cord of human and mammals Recovery of motor functions after spinal cord lesion : experimental approaches and prospects Role of the spinal cord in the control of sexual functions : experimental physiology and pharmacolgy Sensory function recovery in a spinal injury repair model Lunch
S. ROSSIGNOL, Canada J.HOUNSGAARD, Denmark F. CLARAC, France. J.Y. BARTHE, France F. GIULIANO, France M.NIETO SAMPEDRO, Spain
Afternoon 2 Neural Regeneration 14.00 15.00 16.00 16.30 17.00 17.30 18.00 18.30 19.00
Chairperson Ch. HENDERSON, France Poster session Regulation of the survival and death of developing motoneurons Coffee break Factors affecting motoneuron form and growth A robust potential for CNS axon regeneration exists beyond the glial scar Overcoming inhibitors of regeneration in myelin: developing strategies intrinsic to the neuron Repair of respiratory spinal pathways following grafting strategy Axonal regeneration : the obstacles of the glial scar Free
R.W. OPPENHEIM, USA Ch.HENDERSON, France J.SILVER,USA M.T. FILBIN,USA P. GAUTHIER, France M. GIMENEZ, France
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Thursday April 11 Morning 3 Motoneuron Diseases 09.00 10.00 10.30 11.00 11.30 12.00 12.30 13.00
Chairperson D. PRICE, USA Cellular and molecular mechanisms of neuronal death The value of transgenic and gene targeted models for experimental therapeutics in neurodegenerative diseases Coffee break New data on Amyotrophic Lateral Sclerosis in Europe Spinal Muscular Atrophy : recent advances and future prospects Kennedy disease and androgene receptors Mechanism of degeneration in transgenic mouse model of ALS Lunch
D. GREEN, USA D. PRICE,USA V. MEININGER, France J.MELKI, France. S. LUMBROSO, France J.P. JULIEN, Canada
Afternoon 4 Emerging Technologies in CNS pathophysiological Research 14.00 15.00 16.00 16.30 17.00 17.30 18.00 18.30 20.30
Chairperson : D. STROSBERG, France Poster Session Neural stem cells Coffee break Microarrays and neuroscience :development of innovative methods Viral vectors for therapeutic gene transfer Adult CNS Stem cells :potential for cell-based therapies developping strategies intrinsic to the neuron The experience of Hybrigenics Combinatory chemistry : an overview Gala dinner
R. McKAY, USA. S. DUMAS, France. O. DANOS, France L.SHIHABUDDIN, USA D. STROSBERG, France A.WAGNER, France.
Friday April 12
Morning 5 Recent Advances in Imaging 09.00 10.00 10.30 11.00 11.30 12.00 12.30 13.00
Chairperson : R.TURNER, U.K. Ethical issues in CNS Repair Imaging in human patients Coffee break New advances in small animal, in vivo radioimaging Non-invasive imaging techniques for the follow-up of spinal cord injury in small mammals Functional MRI in spine trauma The scope of Functional MRI Lunch
R.M. QUENCER,USA Ph. LANIECE, France M. GAVIRIA, France P. SABBAH, France R.TURNER, U.K.
Afternoon 6 Clinical Research in Spine Trauma 14.00 15.00 16.00 16.30 17.00 17.30 18.00 18.30 19.00
Chairperson :Ph. MENEI, France Poster Session Methodology Results and of clinical trials Coffee break Repair of avulsed ventral spinal ner ve roots after brachial plexus injury : new surgical strategies in humans «Laufband» therapy in incomplete spinal cord injury Advanced neuroprostheses and surgery for tetraplegia A randomised trial of corticosteroïds in head injury – The CRASH trial Some neural substrates of learning in the mammalian spinal cord END
M.TADIÉ, France H.D. FOURNIER, France A.WERNIG, Germany M.KEITH, USA J.WASSERBERG, U.K. R.EDGERTON, USA
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General information Registration fee Before December 31st After December 31st 450 / (approx $395) 540 / (approx $475) 190 / (approx $170) 190 / (approx $170) 60 / (approx $55)
Regular Student (special one rate) : Accompagnying person : Gala dinner For participants, registration fee include ParisDeauville transfer by shuttle on Tuesday April 9 and Friday April 12, abstract books and congress material, attendance to scientific sessions, coffee breaks, three lunches.
For accompagnying persons, registration fee include ParisDeauville transfer by shuttle on Tuesday 9 and Friday 12, the two excursions on Wednesday April 10 afternoon and Friday April 11 (one day).
Payment Payment must be made in Euro currency including banking charges by credit card, transfer or cheque ordered to IRME forwarded with the Registration form to IRME Conference Secretariat.
Welcoming reception
Hotel accomodation
Tuesday April 9, 2002
Most of the selected hotels are within walking distance from the C.I.D. For your convenience, we have negociated through the CID special discount rate for hotel rooms. (See hotel rate on the accomodation form)
guarantee booking. Rooms will be allocated on a first come, first served basis in the requested categor y.
Social Program All participants and accompagnying persons are invited to the welcoming reception in the evening.
Gala dinner Thursday 11, 2002 A gala dinner will take place on Thursday 15. Places are limited. Please reserve through the Registration form (Price : 60 / (approx $55).
Preferences must be indicated on the enclosed accommodation form. The payment of a deposit is necessary to
Hotel booking deposit Separate payment accepted by credit card, transfer or cheque ordered to CID forwarded with the Accomodation form to CID Congress Department. Separate confirmation will be returned by mail. Cancellation and refund Registration : 75 % of the fees will be reimbursed for cancellation received by letter or by fax, before March 1st, 2002. No refund will be made after this date. Hotel reservation : a refund of the deposit will be made after the congress for cancellation received by letter of by fax before March 15, 2002. No refund will be made after this date.
Map Nbr **** *** *** ** ** ** ** **
Normandy / Royal Augeval Yacht Club Ibis Helios Continental Cote fleurie Chantilly
1 2 3 5 5 6 7 7
x x x x
A very limited number of rooms for 3 or 4 persons is offered by Côte Fleurie and Chantilly hotels. Priority will be given to students.
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Information about Deauville The meeting will be held in Deauville, the most famous resort of the Normandy coast, two hours drive from Paris.All scientific sessions will take place in the "Centre International de Deauville" (C.I.D.) The CID is a wonderful work-place, located between the Casino and the boardwalk, right on the beach, a short distance from the best hotels and the downtown area. www.deauville.org
Climate :
Wednesday April 10 (afternoon) Bus trip on the "Corniche Normande" :Visit of Honfleur and Boudin Museum (preimpressionist and contemporary paintings).Tea-time at «La Petite Chine». Or bus trip through the «Pays d’Auge».Visit of a stately manor and of a traditional distillery : tasting accompagnied by traditionnal pastries.
How to reach Deauville ? by road : 190 kilometers from Paris on the A13 highway (in two hours).
by sea link : daily sailings from Great Britain by Britany Ferries : Porthsmouth - Ouistreham : Phone : +33(0)2 31 36 36 36 Southampton - Porthsmouth Le Havre : Phone : +33 (0)2 35 19 78 50 by shutlle : A special bus will be available in the Air France terminal in Paris at "Porte Maillot" around 5 p.m. on Tuesday April 9. Most of the the transatlantic and european flights arrive in Paris in the morning or in the early afternoon. Possibility of return on Friday April 12 : Departure around 7.30 p.m. from the CID (arrival time in Paris at Porte Maillot around 9.30 p.m.)You are kindly requested to reserve through the Registration form.
Its history, its charm, its gastronomy Social program for accompagnying persons
In April, the weather is often sunny but can be occasionnaly rainy.The average temperature is 17°C.
by train : Paris St Lazare Deauville railway station in two hours (daily connection in the morning and the afternoon) SNCF Information : Phone : 08 36 35 35 35, Minitel 3615 code SNCF, http:// www.sncf.com
Discovery and exploration of the Normandy
Relaxation and entertainment A wide variety of facilities (golf, polo, riding, tennis, thalassotherapy and rental of car) are possible at special discount rate. Information could be provided at the Congress desk.
A minimum of 25 persons is necessary for these excursions. You are requested to reserve through the Registration form.
Friday April 12, (one day) Bus trip in the Bay of Saint Michael Mount. Panoramic stop at Avranches - Lunch at the Mount and guided visit of the famous abbey. Optional Post-Congress Program
Saturday April 13 A day trip on the D. Day beaches : visit of the landing museum in Arromanches Lunch in a country inn. Stop to the «Pointe du Hoc», a german fortified strategic place conquered by the rangers on June 6, 1944 morning, and visit of the american militar y cemetery of Colleville sur Mer. Price : 70 / (approx $65) A minimum of 25 persons is necessary for these excursions. You are requested to reserve through the Registration form.
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The French Institute for Spinal Cord Research (IRME) is a non profit organization founded in 1984 by Jean Delourme whose grand’son,then 20 years old, severely injured his spinal cord in a car crash and became quadriplegic. IRME is a member of the International Campaign for Cures of spinal cord Paralysis (ICCP). www.campaignforcure.org
Trustees Board Founder Jean DELOURME Past-President of Houdé Laboratories President Gabriel MAILLARD Past President of the French Academy of Pharmacy Vice-Presidents Jacques CONS,M.D. Past President of Roussel Laboratories Henri HEPNER,M.D. Neurosurgeon,Nancy Treasurer Gérard VIDALENCHE Founder of Investir Magazine Members Yvon ASCOLA Past Vice-President of the Lions Club International DM 103 Jean-Paul CHIRON Professor , Faculty of Pharmacy,Tours Patrick CHOAY President of BAILLY-SPEAB Laboratories Renaud DELOURME Chairman and Managing Director of Montparnasse Editions Cyr GAIGNAULT Member of the French Academy of Pharmacy Bernard MOREL Notary, Paris Jean OUSTRIN Past International Director of the Lions Clubs Georges PLACET Past President of the Lions Club International DM 103 France Jean-Marie VIAL Past Gouvernor of the the Lions Club District 103 France S.E.
Scientific Advisory Board Jean-Marie ANDRÉ,M.D. Dept of Physical Medicine and Rehabilitation,CRAM,Nancy
Centre of Mulhouse Past President of the International Medical Society of Paraplegia (IMSOP) Chairman of the Educational Committee of IMSOP
Jacques BRUNON,M.D. Dept of Neurosurgery, Bellevue Hospital, Saint-Etienne Chairman of the French Speaking Spine Neurosurgical Society
Michel GUILLAUMAT, M.D. Orthopaedic Surgeon,Ellen Poidatz Foundation
Bernard BUSSSEL,M.D. Dept of Neurological Rehabilitation, Raymond Poincaré Hospital,Garches
Hans HULTBORN,M.D. Dept of Medical Physiology, Panum Institute, University of Copenhagen,Denmark
François CLARAC, PhD. Dept of Neurobiology and mo vements CNRS,Marseille
Michel HAMON,PhD. Unit of NeurophysioPharmacology, Faculty of Medicine Pitié-Salpétrière, Paris President of the French Society for Neurosciences
Paul DOLLFUS,M.D. Honorary Chief Consultant,Rehailitation
Pierre MAGISTRETTI,M.D.,PhD. Neurological Research Laboratory, Faculty of Medicine, Lausanne, Switzerland Gustave MOONEN,M.D.,PhD. Dept of Neurology, CHU Sart Tilman, University of Liege, Belgium Brigitte PERROUIN-VERBE,M.D. Dept of Rehabilitation, St Jacques Hospital,Nantes Secretary of the International French Speaking Action Groups for Paraplegia (AFIGAP) Geoffrey RAISMAN,M.D. Dphil Oxford Division of Neurobiology, National Institute for Medical Research,London,UK
Information :IRME - 45,rue Vineuse - 75116 Paris - France Phone +33 (0)1 44 05 15 43 - Fax +33 (0)1 44 05 15 22 e-mail :
[email protected] - www.irme.org
