André Estévez-Torres Laboratoire de photonique et de nanostructures, CNRS route de Nozay, 91460 Marcoussis, France Tel +33 1.69.63.61.61, [email protected]

Date of birth : 11.11.80 Nationality : Spanish Researcher at CNRS

Education July 2007

PhD in Physical and Analytical Chemistry, Université Pierre et Marie Curie, Paris.

June 2003

Masters in Physical Chemistry, Université Pierre et Marie Curie, Paris.

2000–2002

Double degree in Chemistry and Physics, Université Pierre et Marie Curie and École normale supérieure, Paris.

Research 2010–present 2008–2010

2007–2008

2003–2007

Researcher at CNRS at Laboratory for photonics and nanostructures, Marcoussis, France. "Engineering of dynamic reaction networks". Post-doctoral fellow at Department of Physics, Princeton University. Advisor : Robert H. Austin. "Directed evolution of algae in microsystems for efficient production of biodiesel". Post-doctoral fellow at Department of Physics, Kyoto University. Advisor : Kenichi Yoshikawa. "Photo-control of in vitro transcription activity by tuning the conformation of giant DNA". Graduate student (PhD) at Department of Chemistry, École Normale Supérieure. Advisor : Ludovic Jullien. Title : "An electrophoretic microlaboratory to study the coupling between transport and chemical kinetics".

Teaching and mentoring 2012 2012 2011-present 2011-present 2004-2007 2004–present

Teaching Assistant in M2, DNA nanotechnology (3 h), ENSTA ParisTech, Palaiseau. Teaching Assistant in M2, DNA nanotechnology (2 h), Université Paris Sud, Orsay. Teaching Assistant in L3, chemical reactivity (32 h), Ecole normale supérieure, Paris. Examinator of concours d’entrée PC at École normale supérieure, Paris. Teaching Assistant in L1, general chemistry (200 h), Université Pierre et Marie Curie, Paris. Mentor of 9 undergraduate research projects.

Grants and fellowships G3N CNRS (2012), ANR jeunes chercheuses et jeunes chercheurs Dynano (2012-2016), Projets coopératifs avec l’université d’Evry-Val-d’Essonne du PRES UniverSud Microscila (2012-2013), C’nano Ile-de-France Enginets (2012-2013), Triangle de la physique Microgradients (2010-2012), King Abdullah University of Science and Technology postdoctoral fellowship (2008-2010), Japan Society for Progress of Science postdoctoral fellowship (2008), Japan Science and Technology Agency invited researcher (2007-2008), French Research Ministry PhD fellowship (2004-2007), École normale supérieure undergraduate fellowship (20002004).

Publications

– J.-C. Galas, A.-M. Haghiri-Gosnet, A. Estévez-Torres, "A nanoliter-scale open chemical reactor", submitted, 2012. – A. Estévez-Torres, D. Baigl, "DNA compaction : fundamentals and applications", Soft matter, doi :10.1039/c1sm05373f, 2011. – L. Liu, K. Loutherback, D. Liao, D. Yeater, G. Lambert, A. Estévez-Torres, J.C. Sturm, R.H. Getzenberg, R.H. Austin, "A microfluidic device for continuous cancer cell culture and passages with hydrodynamic forces", Lab Chip, 10, 1807–1813, 2010. – A. Estévez-Torres, C. Crozatier, A. Diguet, T. Hara, H. Saito, K. Yoshikawa, D. Baigl, "Sequenceindependent and reversible photocontrol of transcription/expression systems using a photosensitive nucleic acid binder", Proc. Natl. Acad. Sci., 106 , 12219–12223, 2009. – A. Estévez-Torres, T. Le Saux, C. Gosse, A. Lemarchand, A. Bourdoncle, L. Jullien, "Fourier transform to analyse the reaction diffusion dynamics in a microsystem", Lab Chip, 7, 1205–1209, 2008. – M. Sollogoub, S. Guieu, M. Geoffroy, A. Yamada, A. Estévez-Torres, K. Yoshikawa, D. Baigl, "Photocontrol of single-chain DNA conformation in cell-mimicking micro-compartments", ChemBioChem, 9, 1201–1206, 2008. – A. Estévez-Torres, C. Gosse, T. Le Saux, J.-F. Allemand, V. Croquette, H. Berthoumieux, A. Lemarchand, L. Jullien, "Fourier analysis to measure diffusion coefficients and resolve mixtures on a continuous electrophoresis chip", Anal. Chem., 79, 8222–8231, 2007. – A. Estévez-Torres, T. Le Saux, H. Berthoumieux, A. Georges, S. Fernandez, J.-F. Allemand, V. Croquette, A. Lemarchand, L. Jullien, C. Gosse, "Point mutation detection by on-chip diffusion coefficients measurement", Proc. of µTAS, 2007. – A. Bourdoncle, A. Estévez Torres, C. Gosse, L. Lacroix, P. Vekhoff, T. Le Saux, L. Jullien, J.-L. Mergny, "Quadruplex-based molecular beacons as tunable DNA probes", J. Am. Chem. Soc., 128, 11094–11105, 2006.

Invited talks July 2012 May 2012 September 2011 May 2011 May 2011 May 2011 November 2010 November 2010 October 2010 March 2010 November 2007

July 2007

July 2007

May 2007 April 2007 March 2007 September 2005 September 2005 September 2005 September 2005 April 2004

Molecular choreography. Seminar at Laboratoire d’optique et biologie, Ecole polytechnique, Palaiseau, France. Molecular choreography. Seminar at Institut d’électronique, de microélectronique et de nanotechnologie, Villeneuve d’Ascq, France. Engineering reaction networks outside the cell : reactions and reactors. 3rd Workshop on Stochasticity in Biochemical Reaction Networks, Banff, Canada. Engineering reaction networks outside the cell : reactions and reactors. Seminar at Laboratoire de physique des solides, Université Paris sud, Orsay. Engineering reaction networks outside the cell : reactions and reactors. CNRS microfluidics workshop, Lyon. Engineering reaction networks outside the cell : reactions and reactors. Biophysics seminar, Ecole normale supérieure, Paris. Synthetic epigenetics : Sequence-independent photocontrol of gene expression in vitro. Seminar at LIMMS, Institute of Industrial Sciences, Tokyo University. Synthetic epigenetics : Sequence-independent photocontrol of gene expression in vitro.ICORP Seminar at Kyoto University. Synthetic epigenetics : Sequence-independent photocontrol of gene expression in vitro. Seminar at Insitut Joliot-Curie. Ecole normale supériure de Lyon. Sedimentation-driven selection of lipid-producing microalgae APS March meeting, Portland, Oregon. DNA separation and analysis in microsystems : Towards new genotyping technologies ? Seminar at Prof. K. Takeyasu research group. Graduate School of Biostudies, Kyoto University. An electrophoretic microlaboratory to study the coupling between transport and chemical kinetics. Seminar at Prof. J. Cate research group. Department of Chemistry, University of California Berkeley. An electrophoretic microlaboratory to study the coupling between transport and chemical kinetics. Seminar at Prof. R. H. Austin research group. Department of Physics, Princeton University. Point mutation detection by on-chip diffusion coefficient measurement. Réunion du Réseau Microfluidique et Microsystèmes Fluidiques, Paris, France. Continuous diffusion coefficient measurement in an electrophoresis chip. Seminar of the Department of Physical Chemistry, Universidad de Barcelona, Spain. Continuous diffusion coefficient measurement in an electrophoresis chip. Seminar of the Laboratory of Future, CNRS Rhodia, Bordeaux, France. A highly selective separation method for detecting DNA mutations. 8èmes Journées francophones de jeunes physicochimistes, Marly Le Roi, France. Stochastic resonances and highly selective separation methods. 18th International conference on noise and fluctuations, Salamanca, Spain. Studying DNA diffusion by fluorescence microscopy. Seminar of the Environmental Sciences Department, Universidad de Castilla la Mancha, Toledo, Spain. A separation method based on diffusion. Seminar of the Analytical Chemistry Department, Universidad de Alcalá de Henares, Spain. Kinetic DNA chips : Using fluctuations of a chemical system for controlling movement at the molecular level. Frühjahrssymposium 2004, Heidelberg, Germany.

Contributed posters August 2012 July 2012

18th International Conference on DNA Computing and Molecular Programming, Aarhus, Danemark. Microfluidics 2012, Heidelberg, Germany.

May 2011

Physics and biological systems 2011, Orsay, France.

May 2009

Evolution : the molecular landscape, 74th Cold Spring Harbor Symposium on Quantitative Biology, Cold Spring Harbor, NY. ESF-UB Conference in systems biology, Sant Feliu de Guixols, Spain.

April 2008

October 2006

4th Gordon research conference on physics and chemistry of microfluidics, Waterville Valley, New Hampshire. Journées nationales en nanosciences et nanotechnologies, Besançon, France.

July 2005

Bio-Image summer school, Paris, France.

September 2003

8th International summer school on biophysics : supramolecular structure and function, Rovinj, Croatia.

July 2007