Roche Stéphane Montpellier, FRANCE

Birth: 12/02/1973 - Lyon (69) Married, 1 children

Mobile:

e-mail : [email protected] URL : http://www.sroche.free.fr/ Biotechnologies, Proteomics & Diagnostic

Employment 2003-2009

Montpellier Hospital / CNRS - FRANCE 9 Proteomics Project Manager 9 Diagnostic

2001-2003

Grenoble Hospital - FRANCE 9 9

Quality Assurance Human Cell Therapy

9

CEA / Nice University - FRANCE Genome Stability and radioactive iodide.

9

CEA / CNRS Paris. National Service Low radioactivity level and Genome Stability

9

IBCP / CNRS Lyon, Ph.D. in Biotechnologies Biotherapy in osteoarticular disease & proteomics

2000-2001

1999-2000

1996-1999

Employment as Teacher 2003-2009

Medical University of Montpellier: Teacher in Biochemistry 60H/an Setting-up and manager of optional course « Biotechnologies & Health », 25H.

2001-2003

Medical University of Grenoble: Teacher in regular course and manager of an optional course « Ontogenesis & Differentiation » 40H/an

1996-1999

IBCP CNRS Lyon: Practical research initiation course for technician and graduate student, University of Lyon.

Qualification and Training 2007

Certificate of Medical Communication and Pedagogy, Medical University of Montpellier, France

1999

Ph.D. in “Bioengineering and Health”, University Claude Bernard Lyon (UCBL), Lyon (69), France. "Chondrocytes in culture in high density and in collagen sponges : Application to cartilage repair"

1999

Certificate of “Computer Science for Researcher (Unix and Network Administration)", CNRS IN2P3 Lyon, France.

Interest Diving Reading

CMAS Monitor * (2009). Licence to dive up to minus 60m. Police style books.

Publications

1. Roche, Tiers, Provansal, Seveno, Piva, Jouin, Lehmann, Depletion of one, six, twelve or twenty major blood proteins before proteomic analysis: The more the better?, J Proteomics, sous presse 2. Provansal, Jorgensen, Lehmann, Roche, 2DE Proteomic analysis of Mesenchymal Stem Cells In: Mesenchymal Stem Cell Assays and Applications Edited by:Mohan C. Vemuri, Mahendra S. Rao & Lucas G. Chase. Humana Press, sous presse 3. Gabelle*, Roche*, Lehmann, “CSF biomarkers: Proteomics investigations and clinical applications in neurodegenerative disorders.” Rev Neurol (Paris), 2009, 165(3):213-222 4. Roche, Delorme, Oostendorp, Barbet, Caton, Noel, Boumediene, Papadaki, Cousin, Crozet, Milhavet, Casteilla, Hatzfeld, Jorgensen, Charbord, Lehmann, “Comparative proteomic analysis of human mesenchymal and embryonic stem cells: Towards the definition of a mesenchymal stem cell proteomic signature.” Proteomics, 2009, 9(2):223-232 5. Saintigny, Roche, Meynard, Lopez, “Homologous recombination is involved in the repair response of mammalian cells to low doses of tritium.” Radiat Res, 2008, 170(2):172-183 6. Noel, Caton, Roche, Bony, Lehmann, Casteilla, Jorgensen, Cousin, Cell specific differences between human adipose derived- and mesenchymal- stromal cells despite similar differentiation potentials Corresponding, Experimental Cell Research, 2009, 314(7):1575-84 7. Kastrinaki, Sidiropoulos, Roche, Ringe, Lehmann, Kritikos, Vlahava, Delorme, Eliopoulos, Jorgensen, Charbord, Haupl, Boumpas, Papadaki, Functional, molecular and proteomic characterization of bone marrow mesenchymal stem cells in rheumatoid arthritis Ann Rheum Dis, 2008, 67(6):741-9 8. Roche Gabelle, Lehmann, Proteomics of the Cerebrospinal Fluid, Proteomics Clinical Application, 2008, 2(3): 428-6 9. Roche, Dauvillier, Tiers, Couderc, Piva, Provansal, Gabelle & Lehmann, Auto-antibody profiling on highdensity protein microarrays for biomarker discovery in the cerebrospinal-fluid, J Immunol Methods. Sous presse. 10. Molina, Missé, Roche, Badiou, Cristol, Bonfils, Dierick, Véas, Levayer, Lagrost, Bonnefont-Rousselot, Maurel, Coste and Fournier-Wirth, Identification of ApoC-III as a potential plasmatic biomarker associated with the resolution of HCV infection Proteomics Clinical Application, 2008, 2(5): 751-61 11. Roche, Tiers, Provansal, Piva, Lehmann, Interest of major serum protein removal for Surface-Enhanced Laser Desorption/Ionization - Time Of Flight (SELDITOF) proteomic blood profiling Proteome Sci. 2006, 4:20 12. Roche, Richard, Favrot, Oct-4, Rex-1, and Gata-4 expression in human MSC increase the differentiation efficiency but not hTERT expression J Cell Biochem, 2007 May 15; 101(2):271-80. 13. Lehmann, Dupuy, Peoc'h, Roche, Baudin, Quillard, Berger, Briand, Chwetzoff, Dine, Gonzalo, Dastugue, Seve, Siest, Beaudeux, Présent et futur de la Protéomique Clinique Ann Biol Clin (Paris), 2007 SepOct;65(5):463-71. 14. Roche, Reynes, Tiers, Sabatier, Jouin, Molinaru, Lehmann, Comparison between surface and bead based matrix-assisted laser desorption/ionization profiling technologies using a single bioinformatics algorithm Clinical Proteomics, 2006 2(9):145-152 15. Roche, Provansal, Tiers, Jorgensen, Lehmann, Proteomics of primary mesenchymal stem cells Regenerative Medecine, 2006, 1(4):511-517 16. Freyria, Roche, Ronzière, Herbage, Ascorbate modulation of bovine chondrocyte growth, matrix protein gene expression and synthesis in three-dimensional collagen sponges Biomaterials, 2003; 24; 851-861. 17. Roche, Ronzière, Herbage, Freyria, Use of cross-linked and noncross-linked collagen sponges seeded with bovine chondrocytes to produce cartilage equivalent Biomaterials, 2001; 22; 9-18. 18. Freyria, Ronzière, Roche, Rousseau, Herbage, Regulation of growth, protein synthesis, and maturation of fetal bovine epiphyseal chondrocytes grown in high-density culture in the presence of ascorbic acid, retinoic acid, and dihydrocytochalasin B. J Cell Biochem, 1999, 76(1): 84-98 * Co-auteurs