The relationship between alcohol consumption, health indicators and
BACKGROUND: The pattems of total alcohol, beer and wine consumption were evaluated in the. German National Health Surveys. The impact of these habits ...
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,j Order this document In/ .J f$kiemiol 1999 Dec;28(6): 1066-72
The relationship between alcohol consumption, health indicators and mortality in the German population. Hoffmeister
H, Schelp FP, Mensink GB, Dietz E, Bohning D
Freie Universitat Berlin, Institut fur Soziale Medizin, Germany. [Med1 ine record in process] BACKGROUND: The pattems of total alcohol, beer and wine consumption were evaluated in the German National Health Surveys. The impact of these habits on cardiovascular and all-cause mortality as well as cardiovascular risk factors and liver disease parameters was estimated. METHODS: Independent representative samples of the German population ( 15,400 people), and regional samples of the Berlin-Spandau population (2,370 in total), aged 25-69 years, were analysed. The amount and frequency of alcohol consumption was assessed with standardized questionnaires. Biochemical analyses included serum lipids and gamma-glutamyl-transpeptidase (Gamma GT). Multiple analyses of variante were used to determine the relationship between alcohol intake and biochemical parameters. A mortality follow-up of about 7 years was conducted for the Berlin-Spandau population. Proportional hazard models were used to estimate hazard ratios (HR) for ail-cause and cardiovascular mortality. RESULTS: Over 80% of men and 55% of women in Germany drink alcohol on a regular base. The majority of the consumers (65% of men, 87% of women) are light ( l-20 g/day) or moderate (2 l-40 g/day) drinkers. Higher serum high density lipoprotein (HDL)-cholesterol and Gamma GT levels were observed with increasing alcohol intake. In light and moderate drinkers no significant relationship was seen with non-HDL-cholesterol, triglycerides, blood pressure and body mass index, compared to teetotallers. Men who consumed l-20 g alcohol/day had a significantly lower all-cause and cardiovascular mortality. As compared to nondrinkers. the risk was almost 50% lower. CONCLUSION: The results suggest that light (and possibly moderate) alcohol consumption reduces the risk of cardiovascular and total mortality risk and is favourably related to HDL-cholesterol
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