• Preheats, De-aerates and Dispenses Dissolution Media, Including Surfactants
Media Prep Station
The unit uniquely mixes, heats, and degasses dissolution media with surfactant concentrations as high as 3% at the rate of 8 liters in 15 minutes.
• Acid, Buffer, or Surfactant Mixing A second input channel for either Hydrochloric Acid (up to 36%), buffer, or surfactant is available, which permits the automatic mixing of media to the desired concentration, eliminating user error.
• Preheating of Media Test start-up time is reduced as the system preheats the media to the desired temperature, up to 45°C, with an accuracy of ±2°C.
• Highly Accurate Gravimetric Dispensing The unit exceeds all requirements outlined
Absolute Precision
in the USP or EP for dispensing accuracy (±1.0%), therefore eliminating error.
The DissoPrep X8 Media Prep Station operates in accordance with the guidelines of the USP and the EP, as well as GLP and GMP guidelines. Media is filtered, heated to the desired temperature, degassed under vacuum, mixed with up to 2 components, stirred, and precisely dispensed in individual volumes. All dispensing events are controlled by a precision load cell and the results are documented on an external printer or PC. The unit processes up to 8 liters of dissolution media within 15 minutes. Highly precise dispensing requires approximately 25 seconds per 1000 mL volume. With the internal 8L storage tank, media can be prepared while the dissolution test is running. The target dispensing volumes are user selectable between 150 and 8000 mL with 1 mL resolution.
DissoPrep X8 Specifications Dosing Volume
150 – 8000 mL per vessel, 1 mL increments
Internal Tank Volume
8000 mL
Heating Range
Up to 45°C, settable in 0.1°C increments
Temperature Accuracy
±2°C
Input Channels
One for water or pre-mixed media, and one for acid, buffer, or surfactant
Maximum Acid Concentration
36% hydrochloric acid concentration at the acid input 0.5% concentration from mixed media input/output
Dispensing Principle
Pressure and vacuum-forced delivery which is gravimetrically controlled
Dispensing Accuracy
Better than ±5 g
Degassing
Under vacuum, 700 mb minimum
Mixer
Magnetic stirrer
Mixing Accuracy
