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ISBN 1-58706-096-5 © 2005 LANDES BIOSCIENCE Prepublication price: $119; List Price: $139; To order, visit http://www.landesbioscience.com
BIOSCIENCE
Genetically Modified Mosquitoes for Malaria Control Christophe Boëte Institut de Recherche pour le Développement (I.R.D) Laboratoire Génétique et Evolution des Maladies Infectieuses Montpellier, France EPIDEMIOLOGICAL AND EVOLUTIONARY CONSEQUENCES OF THE USE OF GM MOSQUITOES
MALARIA SITUATION 1. Malaria Situation in the Beginning of the 21st Century Mahamadou A. Thera, Abdoulaye A. Djimdé, Alassane Dicko, Mahamadou Diakité, Kassoum Kayentao, Boubacar Traoré, Amagana Dolo and Ogobara K. Doumbo
8. The Epidemiological Consequences of Reducing the Transmission Intensity of P. falciparum Hugh Reyburn and Chris Drakeley 9. Malaria Parasite Virulence in Mosquitoes and Its Implications for the Introduction and Efficacy of GMM Malaria Control Programmes Heather Ferguson, Sylvain Gandon, Margaret Mackinnon and Andrew Read
2. Malaria and Structural Adjustment: Proof by Contradiction Julie Castro and Damien Millet STATE OF THE ART 3. Immune System Polymorphism: Implications for Genetic Engineering Tom J. Little
10. Thinking Transgenic Vectors in a Population Context: Some Expectations and Many Open-Questions Christine Chevillon, Richard E. Paul, Thierry de Meeûs and François Renaud
4. Development of a Toolkit for Manipulating Malaria Vectors Flaminia Catteruccia, Anthony E. Brown, Elisa Petris, Christina Scali and Andrea Crisanti
RESEARCH ORIENTATIONS AND ETHICAL ISSUES CONCERNING THE USE OF GM MOSQUITOES FOR MALARIA CONTROL
5. Genetic Complexities in African Malaria Vectors and Their Impact on the Spread of a Transgene Frédéric Simard, Tovi Lehmann, Alessandra della Torre and Didier Fontenille
11. The Genetics of Vector-Host Interactions: The Alternative Strategy for Genetic Engineering for Malaria Control Willem Takken and Carlo Costantini 12. Genetically-Modified Mosquitoes for Malaria Control: Requirements to Be Considered before Field Releases Yeya T. Touré and Bart G.J. Knols
THE SPREAD AND EXPRESSION OF RESISTANCE 6. Advantages and Limitations of Transgenic Vector Control: Sterile Males versus Gene Drivers Christopher Curtis, Paul G. Coleman, David W. Kelly and Diarmid H. Campbell-Lendrum
13. Ethics and Community Engagement for GM Insect Vector Release Darryl Macer
7. Malaria-Refractoriness in Mosquito: Just a Matter of Harbouring Genes? Christophe Boëte
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CONCLUSION 14. GM Mosquitoes: Time to Spread Out of the Scientific Arena Christophe Boëte
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ISBN 1-58706-096-5
